Categories LATEST, Other Industries

Dermira suffers a fatal fall after catastrophic trial fail

Investors are ruthless if companies fail to fulfill their promises – a fact that especially applies to pharma companies. And Dermira learned it the hard way. Shares of the skin specialist tanked almost 60% on Monday after the company announced that its closely-watched experimental acne drug failed to meet the objectives of two phase 3 clinical trials, eliminating hopes raised by the positive results in the previous trial.

Initial success for the new acne drug olumacostat glasaretil, previously termed DRM01, sparked a lot of hype, lifting Dermira’s status higher. But on Monday, the company stunned Wall Street after it reported that its lead drug candidate has been a catastrophic failure.

Dermira stated that its new drug candidate failed to meet the objectives when compared to an inactive topical gel. Though the company is still reviewing the data, it has slashed its plan to continue with DRM01.

This sort of an overreaction from the stock market is expected as a similar trend was noticed when companies like Novan and Foamix Pharmaceuticals witnessed the same fate as that of Dermira. Both the companies had failed during the Phase 3 trials last year, sending the company’s stock spiraling.

This loss proves to be too costly for CEO Tom Wiggans and his team as the company had taken on debt for the first time last year when the acne trial showed some promising results during the mid-stage.

Dermira is now left with two drug candidates to focus on, one of them being DRM04, which is intended to reduce sweating in kids. The company has completed the clinical testing of this treatment and is awaiting an approval from the FDA for marketing. If the company gets an okay from the FDA, the drug will be launched during the second quarter of this year.

Another drug in the pipeline is for skin inflammation, called ‘lebrikizumab’. But before investors pass their judgment on these two projects, it is important to see how the company progresses after the big loss of its acne experiment.

Most Popular

Does Unity Software (U) stock has more room to run?

Last month, the IPO market was in a full swing. IPOs of Snowflake (NYSE: SNOW) and JFROG (NASDAQ: FROG) had an impressive opening day in September, the former creating a

PepsiCo (PEP): Steady snacking habits amid pandemic drive strong quarter for beverage giant

PepsiCo Inc. (NASDAQ: PEP) beat market expectations on both revenue and earnings for the third quarter of 2020. The company saw the momentum continue in its snacks business while the

Does the virus-driven boom make Electronic Arts (EA) a good investment?

With more and more people turning to virtual entertainment sources, amid the virus-related movement restrictions, video game publishers like Electronic Arts (NASDAQ: EA) are witnessing unusually high demand. Not surprisingly,

Tags

Add Comment
Loading...
Cancel
Viewing Highlight
Loading...
Highlight
Close
Top